Ketoconazole shampoo

Ketoconazole is an antifungal drug that works well against dandruff and is also scientifically proven effective against androgenetic alopecia. Ketoconazole is available as a prescription medicine from a pharmacy, but it can also be found in shops (depending on where you live). So what exactly is ketoconazole, and how does it work?

Ketoconazole shampoo

Ketoconazole shampoo

Ketoconazole is an antifungal drug that works well against dandruff and is also scientifically proven effective against androgenetic alopecia. Ketoconazole is available as a prescription medicine from a pharmacy, but it can also be found in shops (depending on where you live). So what exactly is ketoconazole, and how does it work?

Table of contents

Using a good hair growth stimulating shampoo is one of the most accessible options when you are dealing with hair loss. By simply replacing your current shampoo with an effective hair growth shampoo, you can reduce hair loss.

Most shampoos for sale at a drug store do not help against hair loss. In fact, most shampoos contain harmful substances such as parabens, SLS, etc. At the Hair Growth Specialist, we look very critically at hair growth products. We have found a number of shampoos that are really effective against hair loss and also make the scalp healthier. A key ingredient in any hair growth shampoos is Ketoconazole.

Contains 1% Piroctone olamine, also effective against dandruff seven powerful plant extracts including Ecklonia cava and Raspberry ketone the hair growth molecules Caffeine and Niacinamide Argan oil and Cinnamon oil to care for the scalp and hair
Neofollics shampoo contains 12 proven active ingredients to address hair loss in multiple ways. 1% Piroctone olamine, also effective against dandruff seven powerful plant extracts including Ecklonia cava and Raspberry ketone the hair growth molecules Caffeine and Niacinamide Argan oil and Cacorn oil to care for the scalp and hair
The Exfoliating Scalp Therapy Shampoo is clinically proven to bring relief due to its high concentration of active ingredients. The shampoo is suitable for both men and women. Neofollics exfoliating shampoo is part of a scalp treatment

Shampoo containing Ketoconazole

We have one shampoo with Ketoconazole in our product range: Regenepure DR with 1% ketoconazole.

This hair growth stimulating shampoo is much more effective than shampoos like Alpecin and Plantur 39, which contain only one or a few active ingredients, moreover in a low dosage, but which are promoted with a large advertising budget.

Use and dosage

For an effective treatment with ketoconazole shampoo, it is important to follow the correct usage and dosage instructions. You can use Regenepure DR shampoo daily, especially if you suffer from scalp problems like seborrhoeic eczema or severe dandruff.

Do you notice your hair feeling a bit drier over time because of the 1% ketoconazole? Then you can choose to reduce the frequency to 3–4 times a week and not wash your hair on the other days.

Leave the shampoo on for 3-5 minutes to give the active ingredients time to do their job. Afterwards, rinse your hair thoroughly to remove all residues of the shampoo.

What is Ketoconazole?

Ketoconazole was developed for the control of dandruff and itching. Ketoconazole shampoo with a high concentration is a drug that is prescribed to people with seborrheic dermatitis or severe dandruff. Multiple researches to study the effectiveness of this substance have shown that it stimulates hair growth and helps against hereditary hair loss. Various studies have shown that Ketoconazole can be effective against hair loss in three ways:

  • It fights eczema and dandruff (fungicide), creating a better environment to allow the hair to grow
  • Ketoconazole is anti-inflammatory
  • Ketoconazole is a mild DHT reducer (by fighting the formation of 5-alpha reductase on the scalp)

The use of ketoconazole in a shampoo thus has multiple functions. It fights against dandruff and at the same time, it combats hair loss and even stimulates regrowth.

Because Ketoconazole has the effect of slightly drying out the hair, it is recommended to combine Ketoconazole shampoo with a conditioner or to alternate Ketoconazole with a milder shampoo. Leave the shampoo on for a few minutes and then rinse the hair well.

Medical Ketoconazole shampoos such as Nizoral, Aurobindo, Actavis and Mylan contain 2% Ketoconazole. These can only be purchased at the pharmacy on prescription. The high concentration gives a slightly higher efficacy against strong dandruff, but also has a major disadvantage. It dries out the scalp and hair, which means that it can only be used for shorter periods in succession. To inhibit hair loss, long-term use is necessary and therefore a 1% concentration is also effective and much more pleasant to use. This concentration is also still effective against dandruff and seborrhoeic eczema.

Side effects ketoconazole

It is fair to say that side effects may occur when using this shampoo. In some cases, people experience skin symptoms like itching, burning, redness and scaling.

Also, abruptly discontinuing a treatment is not recommended. This is because this can also cause irritation. If you use the shampoo and are not satisfied or experience side effects, it is therefore advisable to phase it out in two to three weeks.

Regenepure DR shampoo
Regenepure DR shampoo
Regenepure
Pros
  • Contains 1% ketoconazole
  • Convenient size
  • Effective against dandruff and itching
Cons
  • Effective against hair loss
  • Can leave hair feeling dry
  • Not ideal for people with dry hair

Scientific studies

The effectiveness of Ketoconazole is proven in several scientific studies:

Ketoconazole compared to Piroctone olamine

Ketoconazole is the most well-known, but it is not the only proven anti-dandruff ingredient in shampoos which stimulates hair growth. Piroctone olamine has a similar effect as Ketoconazole. Research shows (number 3 above) that both ingredients have a positive effect on multiple aspects of hair growth. They have a similar effect on itch and dandruff. Piroctone olamine generally scores better when it comes to hair growth.

In this article, you can read the most important conclusions. 1% Piroctone olamine can be found in Neofollics shampoo, a highly effective alternative to Ketoconazole shampoos.

What about zinc pyrithione?

Another remedy that was strong against dandruff was zinc pyrithione. This is a coordination complex of zinc and pyrithione with antifungal and antibacterial activity.

It reduces bacterial and fungal infections on the scalp that cause dandruff, flaking and itching. This substance has been banned in shampoo and other cleansing products since 1 March 2022.

The European Union has included it on the list of banned substances because of its possible DNA-damaging effects.

The best shampoo against hair loss?

Do you want to buy the best shampoo against hair loss? There are three popular hair growth shampoo Neofollics, Regenepure DR and Revita. We have compared the key differences between the best shampoos against hair loss.

These are the best products:

Contains 1% Piroctone olamine, also effective against dandruff seven powerful plant extracts including Ecklonia cava and Raspberry ketone the hair growth molecules Caffeine and Niacinamide Argan oil and Cinnamon oil to care for the scalp and hair
Neofollics shampoo contains 12 proven active ingredients to address hair loss in multiple ways. 1% Piroctone olamine, also effective against dandruff seven powerful plant extracts including Ecklonia cava and Raspberry ketone the hair growth molecules Caffeine and Niacinamide Argan oil and Cacorn oil to care for the scalp and hair
The Exfoliating Scalp Therapy Shampoo is clinically proven to bring relief due to its high concentration of active ingredients. The shampoo is suitable for both men and women. Neofollics exfoliating shampoo is part of a scalp treatment